In-vitro dissolution dynamic nuclear polarization for sensitivity enhancement of NMR with biological molecules | Chapter individual record

2018, Springer Science Business Media LLC. Dissolution dynamic nuclear polarization (D-DNP) is a technique to prepare hyperpolarized nuclear spin states, yielding a signal enhancement of several orders of magnitude for liquid-state NMR. Here, we describe experimental procedures for the application of D-DNP in high-resolution NMR of biochemical compounds, to determine the time evolution of biochemical processes and intermolecular interactions.

author list (cited authors)
Kim, Y., Wang, Y., Chen, H. Y., & Hilty, C.
publication date
  • Nuclear Magnetic Resonance, Biomolecular
  • Kinetics
citation count