Antimicrobial effects of zinc oxide in an orthodontic bonding agent. | Academic Article individual record
abstract

OBJECTIVE: To test the null hypothesis that the addition of zinc oxide (ZnO) has no effect on the antimicrobial benefits and shear bond strength of a light-cured resin-modified glass ionomer. MATERIALS AND METHODS: ZnO was added to Fuji Ortho LC to create mixtures of 13% ZnO and 23.1% ZnO. Specimen discs of the modified bonding agent were incubated with Streptococcus mutans for 48 hours in a disc diffusion assay that was used to measure zones of bacterial inhibition. In addition, brackets were bonded to bovine deciduous incisors with the modified bonding agents, and shear bond strength was evaluated with a universal testing machine. RESULTS: The modified samples showed that antimicrobial activity increased as the concentration of ZnO increased. There were significant differences (P < .05) in antimicrobial activity. Post hoc tests showed that the antibacterial effects were 1.6 times greater with 23.1% ZnO than with 13% ZnO. There was no difference between Transbond and 0% ZnO (the negative control). After 1 month of daily rinsing, the antibacterial effects of 23.1% ZnO and 13% ZnO decreased 65% and 77%, respectively, but both maintained significant effects over the negative controls. There were no significant differences (P = .055) in shear bond strength between any of the mixture comparisons. CONCLUSIONS: The incorporation of ZnO into Fuji Ortho LC added antimicrobial properties to the original compound without significantly altering the shear bond strength. ZnO holds potential for preventing decalcification associated with orthodontic treatment.

publication outlet

Angle Orthod

author list (cited authors)
Spencer, C. G., Campbell, P. M., Buschang, P. H., Cai, J., & Honeyman, A. L.
publication date
2009
keywords
  • Streptococcus Mutans
  • Tooth, Deciduous
  • Cattle
  • Orthodontic Brackets
  • Zinc Oxide
  • Dental Bonding
  • Surface Properties
  • Animals
  • Temperature
  • Colony Count, Microbial
  • Aluminum Silicates
  • Materials Testing
  • Water
  • Time Factors
  • Dental Stress Analysis
  • Resin Cements
  • Glass Ionomer Cements
  • Incisor
  • Anti-Infective Agents
  • Shear Strength
  • Stress, Mechanical
  • Acrylic Resins
  • Random Allocation
citation count

46

PubMed ID
19216586
identifier
300166SE
Digital Object Identifier (DOI)
start page
317
end page
322
volume
79
issue
2