NONSPECIFIC EXCITATORY EFFECTS OF MORPHINE - REVERSE-ORDER PRECIPITATED WITHDRAWAL AND DOSE-DOSE INTERACTIONS | Academic Article individual record
abstract

We recently reported that, in naive mice pretreated with naloxone, morphine can cause withdrawal-like signs that seemingly are not mediated by \"opiate\" receptors. Such results were confirmed and extended here with another mouse strain. Repetitive vertical jumping could occur respective of injection sequence and depended on dose and dose ratio of the two drugs.

author list (cited authors)
STEVENS, D. R., & KLEMM, W. R.
publication date
1981
publisher
Springer Nature Publisher
published in
keywords
  • Mice, Inbred ICR
  • Mice
  • Akathisia, Drug-Induced
  • Naloxone
  • Drug Interactions
  • Animals
  • Time Factors
  • Morphine
  • Male
  • Humans
  • Receptors, Opioid
  • Substance Withdrawal Syndrome
altmetric score

3.0

citation count

1

PubMed Central ID
6275445
identifier
190865SE
Digital Object Identifier (DOI)
start page
210
end page
211
volume
75
issue
2